Genetic risk factors for venous thromboembolism

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Risk factors for venous thromboembolism.

Until the 1990s, venous thromboembolism (VTE) was viewed primarily as a complication of hospitalization for major surgery (or associated with the late stage of terminal illness). However, recent trials in patients hospitalized with a wide variety of acute medical illnesses have demonstrated a risk of VTE in medical patients comparable with that seen after major general surgery. In addition, epi...

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Risk factors for venous thromboembolism.

Risk factors for venous thromboembolism (VTE) are often modifiable and overlap with risk factors for coronary artery disease. Encouraging our patients to adopt a heart-healthy lifestyle by abstaining from cigarettes, maintaining lean weight, limiting red meat intake, and controlling hypertension might lower the risk of pulmonary embolism and deep vein thrombosis (DVT), although a cause-effect r...

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Identifying risk factors for venous thromboembolism.

Our understanding of risk factors associated with the development of venous thromboembolism (VTE) has increased steadily over the past 20 years. In the 1980s, the development of VTE was conceptualized in the context of the factors in Virchow’s classic triad that he believed led to venous thrombosis. These factors were injury to the endothelium, alteration in blood flow (particularly stasis/immo...

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Multilocus Genetic Risk Scores for Venous Thromboembolism Risk Assessment

BACKGROUND Genetics plays an important role in venous thromboembolism (VTE). Factor V Leiden (FVL or rs6025) and prothrombin gene G20210A (PT or rs1799963) are the genetic variants currently tested for VTE risk assessment. We hypothesized that primary VTE risk assessment can be improved by using genetic risk scores with more genetic markers than just FVL-rs6025 and prothrombin gene PT-rs1799963...

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Postpartum venous thromboembolism: incidence and risk factors.

OBJECTIVE To calculate incidence of postpartum venous thromboembolism by week after delivery and to examine potential risk factors for venous thromboembolism overall and at different times during the postpartum period. METHODS A deidentified health care claims information database from employers, health plans, hospitals, and Medicaid programs across the United States was used to identify deli...

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ژورنال

عنوان ژورنال: Expert Review of Hematology

سال: 2020

ISSN: 1747-4086,1747-4094

DOI: 10.1080/17474086.2020.1804354